Pd2(dotpm)2



DEPARTMENT OF CHEMISTRY

DePaul DEPAUL UNIVERSITY


   PdCl2otppm





QUINETTA D. SHELBY 

Associate Professor of Chemistry
Inorganic and Organic Chemistry
QDS


Dr. Shelby received her B.S. degree from the University of Chicago and her Ph.D. degree from the University of Illinois at Urbana-Champaign.  She was awarded a National Institutes of Health Research Supplement for Minority Individuals in Postdoctoral Training, and conducted postdoctoral research at Yale University.  Dr. Shelby joined the faculty at Chicago State University in 2000, and she joined the DePaul University chemistry faculty in 2004.

Department of Chemistry
DePaul University                       
McGowan South 309A
1110 West Belden Avenue
Chicago, IL 60614-3251

Phone:
773-325-7402 (office, AJM 309A)
 773-325-7410 (lab, AJM 310)

Fax: 773-325-7421

Email: qshelby@depaul.edu

Courses
 Research
 Group Members



Allylation of aldehydes using allylsilane substrates is important because the reaction forms homoallylic alcohols, which are useful intermediates in the synthesis of natural products.  Two key challenges inherent in this reaction are low reactivity of allylsilanes and lack of stereoselectivity in product formation.  Research in the Shelby group focuses on using chiral Pd catalysts containing an electronically anionic bidentate ligand to activate the reaction of allylsilanes with aldehydes and to promote the asymmetric synthesis of the homoallylic alcohol products.  These ligands allow us to modify easily the steric, electronic, and chiral characters of the phosphine substituents to study their effects on activation and selectivity.  Our long-term objective is to contribute significantly to the fundamental understanding of principles that will improve catalytic systems for synthetic reactions.


Funding:

 Research in the Shelby Group is supported by an NSF CAREER grant (2006 - 2011) and by DePaul University.


Selected Publications:

Lumbreras, E.; Sisler, E. M.; Shelby, Q. D. "Synthesis, X-ray Crystal Structure, and Reactivity of Pd2(μ-dotpm)2 (dotpm = bis(di-ortho-tolylphosphino)methane)," J. Organomet. Chem. 2010, 695, 201-205.

Badgett, A. H.; Gray, D. L.; Shelby, Q. D. "Dichlorido{di-(2-methylphenyl)[(diphenylphosphino)methyl]phosphine-ĸ2P,P'} palladium(II)", Acta Cryst. 2009, E65, m1233-m1234.

Pitroda, P. P.; Badgett, A. H.; Dickey, G. A.; Gray, D. L.; Shelby, Q. D. "(Di-o-tolylphosphino)methyldiphenylphosphine sulfide," Acta Cryst. 2009, E65, o2307.

Sisler, E. M.; Arias, K.; Gray, D. L.; Shelby, Q. D. "1,1,2,2-Tetrakis(di-o-tolylphosphino)ethane," Acta Cryst. 2009, E65, o2231.

Shelby, Q. D. "1,2,3,4,5-Pentaphenyl-1'-(di-tert-butyl-phosphino)ferrocene," Electronic Encyclopedia of Reagents for Organic Synthesis [Online], John Wiley & Sons, Ltd, Posted September 15, 2008 http://www.mrw.interscience.wiley.com/eros/articles/rn00896/abstract-fs.html.


Last Update: June 14, 2011
Content Disclaimer