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Quinetta
D.
Shelby
Assistant Professor
of Chemistry |
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Quinetta
D.
Shelby
Assistant Professor
of Chemistry |
| DePaul University Department of Chemistry McGowan South 309A 1110 West Belden Avenue Chicago, IL 60614-3251 Phone: 773-325-7402 (office, AJM 309A) 773-325-7410 (lab, AJM 310) Fax: 773-325-7421 Email: qshelby@depaul.edu Shelby Research Group CHE 173 CHE173L LSP120 Spring 2009 Office Hours: ThF 1:00 pm - 2:00 pm or by appointment
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Biography:
Dr. Shelby received her B.S. degree from the University of Chicago and Ph.D. degree from the University of Illinois at Urbana-Champaign. She was awarded a National Institutes of Health Research Supplement for Minority Individuals in Postdoctoral Training, and conducted postdoctoral research at Yale University. She joined the faculty at DePaul University in 2004. Research Interest: Allylation of aldehydes using allylsilane
substrates
is important because the reaction forms homoallylic alcohols, which are
useful
intermediates in the synthesis of natural products. Two key
challenges
inherent in this reaction are low reactivity of allylsilanes and lack
of
stereoselectivity in product formation. Our research focusses on
using
chiral Pd catalysts containing an electronically anionic bidentate
ligand
to activate the reaction of allylsilanes with aldehydes and to promote
the
asymmetric synthesis of the homoallylic alcohol products. These
ligands
allow us to modify easily the steric, electronic, and chiral characters
of
the phosphine substituents to study their effects on activation and
selectivity.
Our long-term objective is to contribute significantly to the
fundamental understanding of principles that will improve catalytic
systems for synthetic reactions.
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