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Quinetta
D. Shelby
Assistant Professor
of
Chemistry |
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Quinetta
D. Shelby
Assistant Professor
of
Chemistry |
| DePaul University Department of Chemistry O'Connell 380 1036 West Belden Avenue Chicago, IL 60614-3251 Phone: 773-325-7402 (office) 773-325-7410 (lab, OC 446) Fax: 773-325-7421 Email: qshelby@depaul.edu Shelby Research Group Autumn 2008 Office Hours: By appointment only
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Biography:
Dr. Shelby received her B.S. degree from the University of Chicago and Ph.D. degree from the University of Illinois at Urbana-Champaign. She was awarded a National Institutes of Health Research Supplement for Minority Individuals in Postdoctoral Training, and conducted postdoctoral research at Yale University. She joined the faculty at DePaul University in 2004. Research Interest: Allylation of aldehydes using allylsilane
substrates is important because the reaction forms homoallylic
alcohols, which are useful intermediates in the synthesis of natural
products. Two key challenges inherent in this reaction are low
reactivity of allylsilanes and lack of stereoselectivity
in product formation. Our research focusses on using chiral Pd
catalysts
containing an electronically anionic bidentate ligand to activate the
reaction
of allylsilanes with aldehydes and to promote the asymmetric synthesis
of
the homoallylic alcohol products. These ligands allow us to
modify
easily the steric, electronic, and chiral characters of the phosphine
substituents
to study their effects on activation and selectivity. Our
long-term
objective is to contribute significantly to the fundamental
understanding
of principles that will improve catalytic systems for synthetic
reactions.
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